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LRIG2 is a growth suppressor of Hec-1A and Ishikawa endometrial adenocarcinoma cells by regulating PI3K/AKT- and EGFR-mediated apoptosis and cell-cycle
Although endometrial cancer is the most common type of gynecological malignancy in developed countries, its molecular etiology is not well understood. Leucine-rich repeat and immunoglobulin-like domain 2 (LRIG2) is an evolutionarily conserved gene, but its functions in the endometrium are unknown. I...
Autores principales: | Suh, Dae-Shik, Park, Si Eun, Jin, Hanyong, Lee, Kangseok, Bae, Jeehyeon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833696/ https://www.ncbi.nlm.nih.gov/pubmed/29358688 http://dx.doi.org/10.1038/s41389-017-0019-1 |
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