Dysfunctional autophagy following exposure to pro-inflammatory cytokines contributes to pancreatic β-cell apoptosis

Type 1 diabetes (T1D) results from β-cell destruction due to concerted action of both innate and adaptive immune responses. Pro-inflammatory cytokines, such as interleukin-1β and interferon-γ, secreted by the immune cells invading islets of Langerhans, contribute to pancreatic β-cell death in T1D. C...

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Detalles Bibliográficos
Autores principales: Lambelet, Martine, Terra, Leticia F., Fukaya, Makiko, Meyerovich, Kira, Labriola, Leticia, Cardozo, Alessandra K., Allagnat, Florent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833699/
https://www.ncbi.nlm.nih.gov/pubmed/29367588
http://dx.doi.org/10.1038/s41419-017-0121-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833699/
https://www.ncbi.nlm.nih.gov/pubmed/29367588
http://dx.doi.org/10.1038/s41419-017-0121-5

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