Cargando…

Dysfunctional autophagy following exposure to pro-inflammatory cytokines contributes to pancreatic β-cell apoptosis

Type 1 diabetes (T1D) results from β-cell destruction due to concerted action of both innate and adaptive immune responses. Pro-inflammatory cytokines, such as interleukin-1β and interferon-γ, secreted by the immune cells invading islets of Langerhans, contribute to pancreatic β-cell death in T1D. C...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lambelet, Martine, Terra, Leticia F., Fukaya, Makiko, Meyerovich, Kira, Labriola, Leticia, Cardozo, Alessandra K., Allagnat, Florent
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833699/ https://www.ncbi.nlm.nih.gov/pubmed/29367588 http://dx.doi.org/10.1038/s41419-017-0121-5

Ejemplares similares

A20 deficiency sensitizes pancreatic beta cells to cytokine-induced apoptosis in vitro but does not influence type 1 diabetes development in vivo
por: Catrysse, L, et al.
Publicado: (2015)

Cystathionine Gamma Lyase Is Regulated by Flow and Controls Smooth Muscle Migration in Human Saphenous Vein
por: Zhao, Shuang, et al.
Publicado: (2023)

Sodium thiosulfate acts as a hydrogen sulfide mimetic to prevent intimal hyperplasia via inhibition of tubulin polymerisation
por: Macabrey, Diane, et al.
Publicado: (2022)

Exposure to the Viral By-Product dsRNA or Coxsackievirus B5 Triggers Pancreatic Beta Cell Apoptosis via a Bim / Mcl-1 Imbalance
por: Colli, Maikel L., et al.
Publicado: (2011)

SKAP2, a Candidate Gene for Type 1 Diabetes, Regulates β-Cell Apoptosis and Glycemic Control in Newly Diagnosed Patients
por: Fløyel, Tina, et al.
Publicado: (2021)

TGF-β1 modulates the homeostasis between MMPs and MMP inhibitors through p38 MAPK and ERK1/2 in highly invasive breast cancer cells
por: Gomes, Luciana R, et al.
Publicado: (2012)

Sodium thiosulfate, a source of hydrogen sulfide, stimulates endothelial cell proliferation and neovascularization
por: Macabrey, Diane, et al.
Publicado: (2022)

Pancreatic β-Cell Death in Response to Pro-Inflammatory Cytokines Is Distinct from Genuine Apoptosis
por: Collier, J. Jason, et al.
Publicado: (2011)

Zinc Oxide Nanoparticles Induce Autophagy and Apoptosis via Oxidative Injury and Pro-Inflammatory Cytokines in Primary Astrocyte Cultures
por: Song, Woo-Ju, et al.
Publicado: (2019)

Cystathionine-γ-lyase overexpression modulates oxidized nicotinamide adenine dinucleotide biosynthesis and enhances neovascularization
por: Kiesworo, Kevin, et al.
Publicado: (2023)

Cytokines in the Progression of Pancreatic β-Cell Dysfunction
por: Wang, Chunjiong, et al.
Publicado: (2010)

Lysosomal dysfunction and autophagy blockade contribute to IMB-6G-induced apoptosis in pancreatic cancer cells
por: Liu, Lu, et al.
Publicado: (2017)

Vascular smooth muscle cells in intimal hyperplasia, an update
por: Déglise, Sébastien, et al.
Publicado: (2023)

Data on the effect of pro-fibrotic cytokine TGF-β on hepatic stellate cell autophagy
por: Thomes, Paul G., et al.
Publicado: (2016)

Profile of pro-inflammatory cytokines in colostrum of nursing mothers at the extremes of reproductive age
por: Ferrari, Denise Vasconcelos de Jesus, et al.
Publicado: (2020)

H5N1 Influenza a Virus Replicates Productively in Pancreatic Cells and Induces Apoptosis and Pro-Inflammatory Cytokine Response
por: Huo, Caiyun, et al.
Publicado: (2018)

Dysfunctional autophagy induced by the pro-apoptotic natural compound climacostol in tumour cells
por: Zecchini, Silvia, et al.
Publicado: (2018)

Generation and characterization of human insulin-releasing cell lines
por: Labriola, Leticia, et al.
Publicado: (2009)

HSPB1 Is Essential for Inducing Resistance to Proteotoxic Stress in Beta-Cells
por: Gomes, Vinícius M., et al.
Publicado: (2021)

Clinical Use of Hydrogen Sulfide to Protect Against Intimal Hyperplasia
por: Macabrey, Diane, et al.
Publicado: (2022)

Clinical Potential of Hydrogen Sulfide in Peripheral Arterial Disease
por: Bechelli, Clémence, et al.
Publicado: (2023)

Role of microRNAs in the age-associated decline of pancreatic beta cell function in rat islets
por: Tugay, Ksenia, et al.
Publicado: (2015)

Reduction of Connexin36 Content by ICER-1 Contributes to Insulin-Secreting Cells Apoptosis Induced by Oxidized LDL Particles
por: Haefliger, Jacques-Antoine, et al.
Publicado: (2013)

Penfluridol suppresses pancreatic tumor growth by autophagy-mediated apoptosis
por: Ranjan, Alok, et al.
Publicado: (2016)

Parthenolide suppresses pancreatic cell growth by autophagy-mediated apoptosis
por: Liu, Weifeng, et al.
Publicado: (2017)

Los (ex) trabajadores de YPF : trayectorias laborales a 20 años de la privatización /
por: Muñiz Terra, Leticia
Publicado: (2012)

Apoptosis and Pro-inflammatory Cytokine Response of Mast Cells Induced by Influenza A Viruses
por: Liu, Bo, et al.
Publicado: (2014)

Hedgehog Signaling Non-Canonical Activated by Pro-Inflammatory Cytokines in Pancreatic Ductal Adenocarcinoma
por: Wang, Yuqiong, et al.
Publicado: (2016)

Profile of Gut Hormones, Pancreatic Hormones and Pro-inflammatory Cytokines in New Zealand Maori
por: Cervantes, Aya, et al.
Publicado: (2018)

Pro-Inflammatory Cytokines Promote the Transcription of Circular RNAs in Human Pancreatic β Cells
por: Kaur, Simranjeet, et al.
Publicado: (2022)

Role for inducible cAMP early repressor in promoting pancreatic beta cell dysfunction evoked by oxidative stress in human and rat islets
por: Favre, D., et al.
Publicado: (2011)

Butyrate Protects Pancreatic Beta Cells from Cytokine-Induced Dysfunction
por: Prause, Michala, et al.
Publicado: (2021)

Immune Dysfunction in HIV: A Possible Role for Pro- and Anti-Inflammatory Cytokines in HIV Staging
por: Akase, Iorhen Ephraim, et al.
Publicado: (2017)

Brain stem death induces pro-inflammatory cytokine production and cardiac dysfunction in sheep model
por: Walweel, K., et al.
Publicado: (2022)

Antitumor Effects of Rapamycin in Pancreatic Cancer Cells by Inducing Apoptosis and Autophagy
por: Dai, Zhi-Jun, et al.
Publicado: (2012)

Intracellular Desmoglein-2 cleavage sensitizes epithelial cells to apoptosis in response to pro-inflammatory cytokines
por: Yulis, Mark, et al.
Publicado: (2018)

HDLs Protect Pancreatic β-Cells Against ER Stress by Restoring Protein Folding and Trafficking
por: Pétremand, Jannick, et al.
Publicado: (2012)

Autophagy and the (Pro)renin Receptor
por: Binger, Katrina J., et al.
Publicado: (2013)

Afatinib induces pro-survival autophagy and increases sensitivity to apoptosis in stem-like HNSCC cells
por: Liu, Xianfang, et al.
Publicado: (2021)

Methylene blue photodynamic therapy induces selective and massive cell death in human breast cancer cells
por: dos Santos, Ancély F., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_eftlkk9268i1lt25nkuo7ipbb4