MIF inhibits the formation and toxicity of misfolded SOD1 amyloid aggregates: implications for familial ALS

Mutations in superoxide dismutase (SOD1) cause amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease caused by the progressive loss of motor neurons in the brain and spinal cord. It has been suggested that toxicity of mutant SOD1 results from its misfolding, however, it is yet uncle...

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Detalles Bibliográficos
Autores principales: Shvil, Neta, Banerjee, Victor, Zoltsman, Guy, Shani, Tom, Kahn, Joy, Abu-Hamad, Salah, Papo, Niv, Engel, Stanislav, Bernhagen, Jurgen, Israelson, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833700/
https://www.ncbi.nlm.nih.gov/pubmed/29371591
http://dx.doi.org/10.1038/s41419-017-0130-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833700/
https://www.ncbi.nlm.nih.gov/pubmed/29371591
http://dx.doi.org/10.1038/s41419-017-0130-4

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