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Osteoblast-targeted delivery of miR-33-5p attenuates osteopenia development induced by mechanical unloading in mice

A growing body of evidence has revealed that microRNAs (miRNAs) play crucial roles in regulating osteoblasts and bone metabolism. However, the effects of miRNAs in osteoblast mechanotransduction remain to be defined. In this study, we investigated the regulatory effect of miR-33-5p in osteoblasts an...

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Detalles Bibliográficos
Autores principales: Wang, Han, Hu, Zebing, Shi, Fei, Dong, Jingjing, Dang, Lei, Wang, Yixuan, Sun, Zhongyang, Zhou, Hua, Zhang, Shu, Cao, Xinsheng, Zhang, Ge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833703/
https://www.ncbi.nlm.nih.gov/pubmed/29415986
http://dx.doi.org/10.1038/s41419-017-0210-5