Lrig1 is a haploinsufficient tumor suppressor gene in malignant glioma

Recently, a genome-wide association study showed that a single nucleotide polymorphism (SNP) —rs11706832—in intron 2 of the human LRIG1 (Leucine-rich repeats and immunoglobulin-like domains 1) gene is associated with susceptibility to glioma. However, the mechanism by which rs11706832 affects glioma...

Descripción completa

Detalles Bibliográficos
Autores principales: Mao, Feng, Holmlund, Camilla, Faraz, Mahmood, Wang, Wanzhong, Bergenheim, Tommy, Kvarnbrink, Samuel, Johansson, Mikael, Henriksson, Roger, Hedman, Håkan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833707/
https://www.ncbi.nlm.nih.gov/pubmed/29391393
http://dx.doi.org/10.1038/s41389-017-0012-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833707/
https://www.ncbi.nlm.nih.gov/pubmed/29391393
http://dx.doi.org/10.1038/s41389-017-0012-8

Ejemplares similares