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Lrig1 is a haploinsufficient tumor suppressor gene in malignant glioma
Recently, a genome-wide association study showed that a single nucleotide polymorphism (SNP) —rs11706832—in intron 2 of the human LRIG1 (Leucine-rich repeats and immunoglobulin-like domains 1) gene is associated with susceptibility to glioma. However, the mechanism by which rs11706832 affects glioma...
Autores principales: | Mao, Feng, Holmlund, Camilla, Faraz, Mahmood, Wang, Wanzhong, Bergenheim, Tommy, Kvarnbrink, Samuel, Johansson, Mikael, Henriksson, Roger, Hedman, Håkan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833707/ https://www.ncbi.nlm.nih.gov/pubmed/29391393 http://dx.doi.org/10.1038/s41389-017-0012-8 |
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