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Let-7c inhibits cholangiocarcinoma growth but promotes tumor cell invasion and growth at extrahepatic sites

Cholangiocarcinoma (CCA) is a cancer type with high postoperative relapse rates and poor long-term survival largely due to tumor invasion, distant metastasis, and multidrug resistance. Deregulated microRNAs (miRNAs) are implicated in several cancer types including CCA. The specific roles of the miRN...

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Detalles Bibliográficos
Autores principales: Xie, Yu, Zhang, Hang, Guo, Xing-Jun, Feng, Ye-Chen, He, Rui-Zhi, Li, Xu, Yu, Shuo, Zhao, Yan, Shen, Ming, Zhu, Feng, Wang, Xin, Wang, Min, Balakrishnan, Asha, Ott, Michael, Peng, Feng, Qin, Ren-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833708/
https://www.ncbi.nlm.nih.gov/pubmed/29445149
http://dx.doi.org/10.1038/s41419-018-0286-6