A novel autophagy inhibitor berbamine blocks SNARE-mediated autophagosome-lysosome fusion through upregulation of BNIP3

Increasing evidences reveal that autophagy inhibitor could enhance the effect of chemotherapy to cancer. However, few autophagy inhibitors are currently approved for clinical application in humans. Berbamine (BBM) is a natural compound extracted from traditional Chinese medicine that is widely used...

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Detalles Bibliográficos
Autores principales: Fu, Ruoqiu, Deng, Qin, Zhang, Hongwei, Hu, Xiaoye, Li, Yunong, Liu, Yanxia, Hu, Jinjiao, Luo, Qingsong, Zhang, Yanhao, Jiang, Xiuxing, Li, Lirong, Yang, Chong, Gao, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833711/
https://www.ncbi.nlm.nih.gov/pubmed/29445175
http://dx.doi.org/10.1038/s41419-018-0276-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833711/
https://www.ncbi.nlm.nih.gov/pubmed/29445175
http://dx.doi.org/10.1038/s41419-018-0276-8

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