TRAF6 regulates EGF-induced cell transformation and cSCC malignant phenotype through CD147/EGFR

TRAF6, a well-known adapter molecule, plays pivotal role in TLR/IL-1R associated signaling pathway. Although TRAF6 has been shown to have oncogenic activity in various malignant tumors, the details remain unclear. In this study, we demonstrated that TRAF6 facilitates Ras (G12V) and EGF-induced cellu...

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Detalles Bibliográficos
Autores principales: Zhang, Xu, Wu, Lisha, Xiao, Ta, Tang, Ling, Jia, Xuekun, Guo, Yeye, Zhang, JiangLin, Li, Jie, He, Yijing, Su, Juan, Zhao, Shuang, Tao, Juan, Zhou, Jianda, Chen, Xiang, Peng, Cong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833715/
https://www.ncbi.nlm.nih.gov/pubmed/29463844
http://dx.doi.org/10.1038/s41389-018-0030-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833715/
https://www.ncbi.nlm.nih.gov/pubmed/29463844
http://dx.doi.org/10.1038/s41389-018-0030-1

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