Association of cytosolic sialidase Neu2 with plasma membrane enhances Fas-mediated apoptosis by impairing PI3K-Akt/mTOR-mediated pathway in pancreatic cancer cells

Modulation of sialylation by sialyltransferases and sialidases plays essential role in carcinogenesis. There are few reports on sialyltransferase, however, the contribution of cytosolic sialidase (Neu2) remains unexplored in pancreatic ductal adenocarcinoma (PDAC). We observed lower expression of Ne...

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Detalles Bibliográficos
Autores principales: Nath, Shalini, Mandal, Chhabinath, Chatterjee, Uttara, Mandal, Chitra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833727/
https://www.ncbi.nlm.nih.gov/pubmed/29434218
http://dx.doi.org/10.1038/s41419-017-0191-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833727/
https://www.ncbi.nlm.nih.gov/pubmed/29434218
http://dx.doi.org/10.1038/s41419-017-0191-4

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