SIRT1 induces epithelial-mesenchymal transition by promoting autophagic degradation of E-cadherin in melanoma cells

Melanoma is highly metastatic, and understanding of its molecular mechanism is urgently needed for the development of therapeutic targets and prognostic assessment for metastatic melanoma. SIRT1 is a nicotinamide adenine dinucleotide (NAD(+))-dependent protein deacetylase, belonging to the mammalian...

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Detalles Bibliográficos
Autores principales: Sun, Ting, Jiao, Lin, Wang, Yangxia, Yu, Yan, Ming, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833732/
https://www.ncbi.nlm.nih.gov/pubmed/29374154
http://dx.doi.org/10.1038/s41419-017-0167-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833732/
https://www.ncbi.nlm.nih.gov/pubmed/29374154
http://dx.doi.org/10.1038/s41419-017-0167-4

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