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CD40L mediated alternative NFκB-signaling induces resistance to BCR-inhibitors in patients with mantle cell lymphoma

Drug resistance is a significant obstacle in cancer treatment and therefore a frequent subject of research. Developed or primary resistance limits the treatment success of inhibitors of the B cell receptor (BCR) pathway in mantle cell lymphoma (MCL) patients. Recent research has highlighted the role...

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Detalles Bibliográficos
Autores principales: Rauert-Wunderlich, Hilka, Rudelius, Martina, Berberich, Ingolf, Rosenwald, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833745/
https://www.ncbi.nlm.nih.gov/pubmed/29367645
http://dx.doi.org/10.1038/s41419-017-0157-6