Histone deacetylase inhibitors protect against cisplatin-induced acute kidney injury by activating autophagy in proximal tubular cells

Histone deacetylase inhibitors (HDACi) have therapeutic effects in models of various renal diseases including acute kidney injury (AKI); however, the underlying mechanism remains unclear. Here we demonstrate that two widely tested HDACi (suberoylanilide hydroxamic acid (SAHA) and trichostatin A (TSA...

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Detalles Bibliográficos
Autores principales: Liu, Jing, Livingston, Man J., Dong, Guie, Tang, Chengyuan, Su, Yunchao, Wu, Guangyu, Yin, Xiao-Ming, Dong, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833747/
https://www.ncbi.nlm.nih.gov/pubmed/29476062
http://dx.doi.org/10.1038/s41419-018-0374-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833747/
https://www.ncbi.nlm.nih.gov/pubmed/29476062
http://dx.doi.org/10.1038/s41419-018-0374-7

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