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Evaluation of autophagy inducers in epithelial cells carrying the ΔF508 mutation of the cystic fibrosis transmembrane conductance regulator CFTR

Cystic Fibrosis (CF) due to the ΔF508 mutation of cystic fibrosis transmembrane conductance regulator (CFTR) can be treated with a combination of cysteamine and Epigallocatechin gallate (EGCG). Since ECGC is not a clinically approved drug, we attempted to identify other compounds that might favourab...

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Detalles Bibliográficos
Autores principales: Zhang, Shaoyi, Stoll, Gautier, Pedro, José Manuel Bravo San, Sica, Valentina, Sauvat, Allan, Obrist, Florine, Kepp, Oliver, Li, Yousheng, Maiuri, Luigi, Zamzami, Naoufal, Kroemer, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833759/
https://www.ncbi.nlm.nih.gov/pubmed/29415993
http://dx.doi.org/10.1038/s41419-017-0235-9