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Pharmacokinetics, distribution and anti-tumor efficacy of liposomal mitoxantrone modified with a luteinizing hormone-releasing hormone receptor-specific peptide

BACKGROUND: A previous study developed a novel luteinizing hormone-releasing hormone (LHRH) receptor-targeted liposome. The aim of this study was to further assess the pharmacokinetics, biodistribution, and anti-tumor efficacy of LHRH receptor-targeted liposomes loaded with the anticancer drug mitox...

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Detalles Bibliográficos
Autores principales: Zhang, Linhua, Ren, Yanqing, Wang, Yong, He, Yingna, Feng, Wei, Song, Cunxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833774/
https://www.ncbi.nlm.nih.gov/pubmed/29520138
http://dx.doi.org/10.2147/IJN.S150512