Ethanol sensitizes hepatocytes for TGF-β-triggered apoptosis

Alcohol abuse is a global health problem causing a substantial fraction of chronic liver diseases. Abundant TGF-β—a potent pro-fibrogenic cytokine—leads to disease progression. Our aim was to elucidate the crosstalk of TGF-β and alcohol on hepatocytes. Primary murine hepatocytes were challenged with...

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Detalles Bibliográficos
Autores principales: Gaitantzi, Haristi, Meyer, Christoph, Rakoczy, Pia, Thomas, Maria, Wahl, Kristin, Wandrer, Franziska, Bantel, Heike, Alborzinia, Hamed, Wölfl, Stefan, Ehnert, Sabrina, Nüssler, Andreas, Bergheim, Ina, Ciuclan, Loredana, Ebert, Matthias, Breitkopf-Heinlein, Katja, Dooley, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833779/
https://www.ncbi.nlm.nih.gov/pubmed/29352207
http://dx.doi.org/10.1038/s41419-017-0071-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833779/
https://www.ncbi.nlm.nih.gov/pubmed/29352207
http://dx.doi.org/10.1038/s41419-017-0071-y

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