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Ubiquitin C decrement plays a pivotal role in replicative senescence of bone marrow mesenchymal stromal cells

Human bone marrow-mesenchymal stromal cells (hBM-MSCs) undergo cellular senescence during in vitro culture. In this study, we defined this replicative senescence as impaired proliferation, deterioration in representative cell characteristics, accumulated DNA damage, and decreased telomere length and...

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Detalles Bibliográficos
Autores principales:	Kim, Jiyeon, Kim, Yonggoo, Choi, Hayoung, Kwon, Ahlm, Jekarl, Dong Wook, Lee, Seungok, Jang, Woori, Chae, Hyojin, Kim, Jung Rok, Kim, Jung Min, Kim, Myungshin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833785/ https://www.ncbi.nlm.nih.gov/pubmed/29382826 http://dx.doi.org/10.1038/s41419-017-0032-5

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