The histone methyltransferase DOT1L inhibits osteoclastogenesis and protects against osteoporosis

Osteoclasts are absorptive cells that play a critical role in homeostatic bone remodeling and pathological bone resorption. Emerging evidence suggests an important role of epigenetic regulation in osteoclastogenesis. In this study, we investigated the role of DOT1L, which regulates gene expression e...

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Detalles Bibliográficos
Autores principales: Gao, Yanpan, Ge, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833786/
https://www.ncbi.nlm.nih.gov/pubmed/29348610
http://dx.doi.org/10.1038/s41419-017-0040-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833786/
https://www.ncbi.nlm.nih.gov/pubmed/29348610
http://dx.doi.org/10.1038/s41419-017-0040-5

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