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Game-changing restraint of Ros-damaged phenylalanine, upon tumor metastasis

An abrupt increase in metastatic growth as a consequence of the removal of primary tumors suggests that the concomitant resistance (CR) phenomenon might occur in human cancer. CR occurs in murine tumors and ROS-damaged phenylalanine, meta-tyrosine (m-Tyr), was proposed as the serum anti-tumor factor...

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Detalles Bibliográficos
Autores principales: Gueron, Geraldine, Anselmino, Nicolás, Chiarella, Paula, Ortiz, Emiliano G., Lage Vickers, Sofia, Paez, Alejandra V., Giudice, Jimena, Contin, Mario D., Leonardi, Daiana, Jaworski, Felipe, Manzano, Verónica, Strazza, Ariel, Montagna, Daniela R., Labanca, Estefania, Cotignola, Javier, D´Accorso, Norma, Woloszynska-Read, Anna, Navone, Nora, Meiss, Roberto P., Ruggiero, Raúl, Vazquez, Elba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833805/
https://www.ncbi.nlm.nih.gov/pubmed/29396431
http://dx.doi.org/10.1038/s41419-017-0147-8