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CAR-T cells: the long and winding road to solid tumors

Adoptive cell therapy of solid tumors with reprogrammed T cells can be considered the “next generation” of cancer hallmarks. CAR-T cells fail to be as effective as in liquid tumors for the inability to reach and survive in the microenvironment surrounding the neoplastic foci. The intricate net of cr...

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Detalles Bibliográficos
Autores principales: D’Aloia, Maria Michela, Zizzari, Ilaria Grazia, Sacchetti, Benedetto, Pierelli, Luca, Alimandi, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833816/
https://www.ncbi.nlm.nih.gov/pubmed/29449531
http://dx.doi.org/10.1038/s41419-018-0278-6