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CAR-T cells: the long and winding road to solid tumors
Adoptive cell therapy of solid tumors with reprogrammed T cells can be considered the “next generation” of cancer hallmarks. CAR-T cells fail to be as effective as in liquid tumors for the inability to reach and survive in the microenvironment surrounding the neoplastic foci. The intricate net of cr...
Autores principales: | D’Aloia, Maria Michela, Zizzari, Ilaria Grazia, Sacchetti, Benedetto, Pierelli, Luca, Alimandi, Maurizio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833816/ https://www.ncbi.nlm.nih.gov/pubmed/29449531 http://dx.doi.org/10.1038/s41419-018-0278-6 |
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