Glycogen synthase protects neurons from cytotoxicity of mutant huntingtin by enhancing the autophagy flux

Healthy neurons do not store glycogen while they do possess the machinery for the glycogen synthesis albeit at an inactive state. Neurons in the degenerating brain, however, are known to accumulate glycogen, although its significance was not well understood. Emerging reports present contrasting view...

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Detalles Bibliográficos
Autores principales: Rai, Anupama, Singh, Pankaj Kumar, Singh, Virender, Kumar, Vipendra, Mishra, Rohit, Thakur, Ashwani Kumar, Mahadevan, Anita, Shankar, Susarla Krishna, Jana, Nihar Ranjan, Ganesh, Subramaniam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833817/
https://www.ncbi.nlm.nih.gov/pubmed/29422655
http://dx.doi.org/10.1038/s41419-017-0190-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833817/
https://www.ncbi.nlm.nih.gov/pubmed/29422655
http://dx.doi.org/10.1038/s41419-017-0190-5

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