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Glycogen synthase protects neurons from cytotoxicity of mutant huntingtin by enhancing the autophagy flux
Healthy neurons do not store glycogen while they do possess the machinery for the glycogen synthesis albeit at an inactive state. Neurons in the degenerating brain, however, are known to accumulate glycogen, although its significance was not well understood. Emerging reports present contrasting view...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833817/ https://www.ncbi.nlm.nih.gov/pubmed/29422655 http://dx.doi.org/10.1038/s41419-017-0190-5 |