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Circular RNA GRB10 as a competitive endogenous RNA regulating nucleus pulposus cells death in degenerative intervertebral disk

Intervertebral disc degeneration (IDD) is an important factor leading to low back pain, but the underlying mechanisms remain poorly understood. Compared with normal nucleus pulposus (NP) tissues, the expression of circ-GRB10 was downregulated in IDD. Furthermore, overexpression of circ-GRB10 inhibit...

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Detalles Bibliográficos
Autores principales: Guo, Wei, Zhang, Bin, Mu, Kun, Feng, Shi-Qing, Dong, Zhan-Yin, Ning, Guang-Zhi, Li, Hao-Ran, Liu, Shen, Zhao, Ling, Li, Yan, Yu, Bing-Bing, Duan, Hui-Quan, Sun, Chao, Li, Yong-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833826/
https://www.ncbi.nlm.nih.gov/pubmed/29476072
http://dx.doi.org/10.1038/s41419-017-0232-z