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Role of c-Abl and nephrin in podocyte cytoskeletal remodeling induced by angiotensin II

Our previous study showed that angiotensin II (Ang II) exposure diminished the interaction between nephrin and c-Abl, then c-Abl mediated SHIP2-Akt pathway in the process of podocyte injury in vivo and vitro. However, the relationship between nephrin and c-Abl was unknown. Recently, various studies...

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Detalles Bibliográficos
Autores principales: Ma, Yiqiong, Yang, Qian, Zhong, Zhentong, Liang, Wei, Zhang, Lu, Yang, Yingjie, Ding, Guohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833834/
https://www.ncbi.nlm.nih.gov/pubmed/29416010
http://dx.doi.org/10.1038/s41419-017-0225-y