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The cytotoxicity of coxsackievirus B3 is associated with a blockage of autophagic flux mediated by reduced syntaxin 17 expression

Coxsackievirus B3 (CVB3) is an important human pathogen linked to cardiac arrhythmias and acute heart failure. CVB3 infection has been reported to induce the formation of autophagosomes that support the viral replication in host cells. Interestingly, our study shows that the accumulation of autophag...

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Detalles Bibliográficos
Autores principales: Tian, Lang, Yang, Yeyi, Li, Chunyun, Chen, Jia, Li, Zhuoying, Li, Xin, Li, Shentang, Wu, Fang, Hu, Zhangxue, Yang, Zuocheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833838/
https://www.ncbi.nlm.nih.gov/pubmed/29445155
http://dx.doi.org/10.1038/s41419-018-0271-0