Predictive and preventive significance of AMPK activation on hepatocarcinogenesis in patients with liver cirrhosis

Metformin has been demonstrated to prevent hepatocellular carcinoma (HCC). Metformin acts mainly by phosphorylation of AMPK. However, the phosphorylation status of AMPK and its role in the prediction and prevention of HCC in cirrhotic patients remains unclear. The phosphorylation status of AMPK (Thr...

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Detalles Bibliográficos
Autores principales: Yang, Xiaoli, Liu, Yan, Li, Menghui, Wu, Hao, Wang, Yunbing, You, Yu, Li, Peizhi, Ding, Xiong, Liu, Chang’an, Gong, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833839/
https://www.ncbi.nlm.nih.gov/pubmed/29449537
http://dx.doi.org/10.1038/s41419-018-0308-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833839/
https://www.ncbi.nlm.nih.gov/pubmed/29449537
http://dx.doi.org/10.1038/s41419-018-0308-4

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