Cargando…

Predictive and preventive significance of AMPK activation on hepatocarcinogenesis in patients with liver cirrhosis

Metformin has been demonstrated to prevent hepatocellular carcinoma (HCC). Metformin acts mainly by phosphorylation of AMPK. However, the phosphorylation status of AMPK and its role in the prediction and prevention of HCC in cirrhotic patients remains unclear. The phosphorylation status of AMPK (Thr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Xiaoli, Liu, Yan, Li, Menghui, Wu, Hao, Wang, Yunbing, You, Yu, Li, Peizhi, Ding, Xiong, Liu, Chang’an, Gong, Jianping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833839/ https://www.ncbi.nlm.nih.gov/pubmed/29449537 http://dx.doi.org/10.1038/s41419-018-0308-4

Ejemplares similares

Hepatocarcinogenesis in liver cirrhosis: imaging diagnosis.
por: Choi, B. I.
Publicado: (1998)

From Liver Cirrhosis to Cancer: The Role of Micro-RNAs in Hepatocarcinogenesis
por: Mohr, Raphael, et al.
Publicado: (2021)

Autophagy-dependent generation of Axin2+ cancer stem-like cells promotes hepatocarcinogenesis in liver cirrhosis
por: Li, J, et al.
Publicado: (2017)

Gadolinium chloride suppresses acute rejection and induces tolerance following rat liver transplantation by inhibiting Kupffer-cell activation
por: WU, YAKUN, et al.
Publicado: (2014)

Hepatocelluar nodules in liver cirrhosis: hemodynamic evaluation (angiography-assisted CT) with special reference to multi-step hepatocarcinogenesis
por: Matsui, Osamu, et al.
Publicado: (2011)

Chronic liver inflammation dominated by interferon-γ can prevent hepatocarcinogenesis
por: Schrader, Jörg, et al.
Publicado: (2012)

Biodistribution Profile of Magnetic Nanoparticles in Cirrhosis-Associated Hepatocarcinogenesis in Rats by AC Biosusceptometry
por: Soares, Guilherme A., et al.
Publicado: (2022)

Dendritic Cell and T Cell Crosstalk in Liver Fibrogenesis and Hepatocarcinogenesis: Implications for Prevention and Therapy of Liver Cancer
por: Lurje, Isabella, et al.
Publicado: (2020)

Re-evaluation of the Carcinogenic Significance of Hepatitis B Virus Integration in Hepatocarcinogenesis
por: Jiang, Suzhen, et al.
Publicado: (2012)

Keratin 17 Suppresses Cell Proliferation and Epithelial-Mesenchymal Transition in Pancreatic Cancer
por: Zeng, Yong, et al.
Publicado: (2020)

Clinicopathological and prognostic significance of PKM2 protein expression in cirrhotic hepatocellular carcinoma and non-cirrhotic hepatocellular carcinoma
por: Liu, Yan, et al.
Publicado: (2017)

Iron-Induced Hepatocarcinogenesis—Preventive Effects of Nutrients
por: Tsuchiya, Hiroyuki
Publicado: (2022)

Activation of Liver FGF21 in hepatocarcinogenesis and during hepatic stress
por: Yang, Chaofeng, et al.
Publicado: (2013)

TACE Combined with HIFU Versus Surgical Resection for Single Hepatocellular Carcinoma with Child-Pugh B Cirrhosis in Overall Survival and Progression-Free Survival: A Retrospective Study
por: Zhang, Qiwei, et al.
Publicado: (2021)

Anticancer effect of caudatin in diethylnitrosamine-induced hepatocarcinogenesis in rats
por: Song, Jie, et al.
Publicado: (2020)

Opposing roles of HDAC6 in liver regeneration and hepatocarcinogenesis
por: Phorl, Sophors, et al.
Publicado: (2022)

STAT3 deficiency prevents hepatocarcinogenesis and promotes biliary proliferation in thioacetamide-induced liver injury
por: Abe, Mitsuhiko, et al.
Publicado: (2017)

Alcohol and hepatocarcinogenesis
por: Taniai, Makiko
Publicado: (2020)

Butaselen prevents hepatocarcinogenesis and progression through inhibiting thioredoxin reductase activity
por: Zheng, Xiaoqing, et al.
Publicado: (2017)

An NF-kappaB- and IKK-Independent Function of NEMO Prevents Hepatocarcinogenesis by Suppressing Compensatory Liver Regeneration
por: Koppe, Christiane, et al.
Publicado: (2019)

Regulation of liver regeneration and hepatocarcinogenesis by suppressor of cytokine signaling 3
por: Riehle, Kimberly J., et al.
Publicado: (2008)

Enzymic retrodifferentiation during hepatocarcinogenesis and liver regeneration in rats in vivo.
por: Curtin, N. J., et al.
Publicado: (1983)

Changes in Carboxylesterase Isoenzymes of Rat Liver Microsomes during Hepatocarcinogenesis
por: Maki, Takako, et al.
Publicado: (1991)

Gradually elevated expression of Gankyrin during human hepatocarcinogenesis and its clinicopathological significance
por: Jing, Hongbiao, et al.
Publicado: (2014)

Senescence and cell death in chronic liver injury: roles and mechanisms underlying hepatocarcinogenesis
por: Xiao, Mengchao, et al.
Publicado: (2017)

GLUTATHIONE S‐TRANSFERASES AND HEPATOCARCINOGENESIS
por: Sato, Kiyomi
Publicado: (1988)

Oxidative stress and hepatocarcinogenesis
por: Fu, Ying, et al.
Publicado: (2018)

AMPK agonist AICAR ameliorates portal hypertension and liver cirrhosis via NO pathway in the BDL rat model
por: Hu, Liangshuo, et al.
Publicado: (2019)

Cooperation between liver-specific mutations of pten and tp53 genetically induces hepatocarcinogenesis in zebrafish
por: Luo, Juanjuan, et al.
Publicado: (2021)

Loss of heterozygosity at D8S262: an early genetic event of hepatocarcinogenesis
por: Zhu, Qiao, et al.
Publicado: (2015)

Prognostic significance of nonprotein respiratory quotient in patients with liver cirrhosis
por: Nishikawa, Hiroki, et al.
Publicado: (2017)

Treg/Th17 imbalance and its clinical significance in patients with hepatitis B-associated liver cirrhosis
por: Lan, Yong-Ting, et al.
Publicado: (2019)

Changes in intestinal microbiota of HBV-associated liver cirrhosis with/without hepatic encephalopathy
por: Hua, Xiaoli, et al.
Publicado: (2022)

Deferasirox, an oral iron chelator, prevents hepatocarcinogenesis and adverse effects of sorafenib
por: Yamamoto, Naoki, et al.
Publicado: (2016)

The Novel Nutraceutical KJS018A Prevents Hepatocarcinogenesis Promoted by Inflammation
por: Huynh, Do Luong, et al.
Publicado: (2018)

Quantifying Liver Cirrhosis by Extracting Significant Features from MRI T2 Image
por: Hshiao, Ming-Hong, et al.
Publicado: (2012)

Molecular Targets in Hepatocarcinogenesis and Implications for Therapy
por: Wu, Meng-Yu, et al.
Publicado: (2018)

Factors associated with significant liver necroinflammation in chronic hepatitis B patients with cirrhosis
por: Chen, Sheng-Sen, et al.
Publicado: (2016)

The Mutational and Transcriptional Landscapes of Hepatocarcinogenesis in a Rat Model
por: Chen, Zhiao, et al.
Publicado: (2020)

Prevalence, association, and prognostic significance of polypharmacy and sarcopenia in patients with liver cirrhosis
por: Hanai, Tatsunori, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_peahmcc9b7cbmn66r3neqkua9v