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The chemokine receptor CCR10 promotes inflammation-driven hepatocarcinogenesis via PI3K/Akt pathway activation

G-protein-coupled receptor (GPCR)-related proteins are dysregulated and the GPCR CC-chemokine receptor 10 (CCR10) is significantly upregulated in inflammation-driven HCC. However, CCR10′s role in inflammation-driven hepatocarcinogenesis remains unknown. The aim of this study was to evaluate the role...

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Detalles Bibliográficos
Autores principales: Wu, Qiong, Chen, Jin-xian, Chen, Yu, Cai, Li-li, Wang, Xiao-zhong, Guo, Wu-hua, Zheng, Jian-feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833857/
https://www.ncbi.nlm.nih.gov/pubmed/29445190
http://dx.doi.org/10.1038/s41419-018-0267-9