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Interleukin 4 modulates microglia homeostasis and attenuates the early slowly progressive phase of amyotrophic lateral sclerosis

Microglia activation is a commonly pathological hallmark of neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS), a devastating disorder characterized by a selective motor neurons degeneration. Whether such activation might represent a causal event rather than a secondary epipheno...

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Detalles Bibliográficos
Autores principales: Rossi, Chiara, Cusimano, Melania, Zambito, Martina, Finardi, Annamaria, Capotondo, Alessia, Garcia-Manteiga, Jose Manuel, Comi, Giancarlo, Furlan, Roberto, Martino, Gianvito, Muzio, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833860/
https://www.ncbi.nlm.nih.gov/pubmed/29445154
http://dx.doi.org/10.1038/s41419-018-0288-4