Epigenetic inhibition of Wnt pathway suppresses osteogenic differentiation of BMSCs during osteoporosis

Disrupted Wnt signaling in osteoblastic-lineage cells leads to bone formation defect in osteoporosis. However, the factors repressing Wnt signaling are unclear. In our study, we found that Wnt signaling was suppressed persistently in bone marrow-derived mesenchymal stem cells (BMSCs) during osteopor...

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Detalles Bibliográficos
Autores principales: Jing, Huan, Su, Xiaoxia, Gao, Bo, Shuai, Yi, Chen, Ji, Deng, Zhihong, Liao, Li, Jin, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833865/
https://www.ncbi.nlm.nih.gov/pubmed/29416009
http://dx.doi.org/10.1038/s41419-017-0231-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833865/
https://www.ncbi.nlm.nih.gov/pubmed/29416009
http://dx.doi.org/10.1038/s41419-017-0231-0

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