Cargando…

FGF1 induces resistance to chemotherapy in ovarian granulosa tumor cells through regulation of p53 mitochondrial localization

Ovarian cancer remains associated with a high mortality rate and relapse is too frequently seen after chemotherapeutic treatment of granulosa cell tumors (GCTs) or epithelial ovarian cancers (EOCs). It is thus of major importance to progress in the knowledge of the molecular mechanisms underlying ch...

Descripción completa

Detalles Bibliográficos
Autores principales: Manousakidi, Sevasti, Guillaume, Arnaud, Pirou, Caroline, Bouleau, Sylvina, Mignotte, Bernard, Renaud, Flore, Le Floch, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833868/
https://www.ncbi.nlm.nih.gov/pubmed/29467390
http://dx.doi.org/10.1038/s41389-018-0033-y