Comparison of the Pharmacokinetics of Droxidopa After Dosing in the Fed Versus Fasted State and with 3-Times-Daily Dosing in Healthy Elderly Subjects

BACKGROUND: Droxidopa is an oral prodrug of norepinephrine approved for the treatment of symptomatic neurogenic orthostatic hypotension. This two-part, randomized, crossover study evaluated the 24-h pharmacokinetic profile of droxidopa in 24 healthy elderly subjects. METHODS: Noncompartmental analys...

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Detalles Bibliográficos
Autores principales: Chen, Jack J., Hewitt, L. Arthur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833910/
https://www.ncbi.nlm.nih.gov/pubmed/29392574
http://dx.doi.org/10.1007/s40268-018-0226-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833910/
https://www.ncbi.nlm.nih.gov/pubmed/29392574
http://dx.doi.org/10.1007/s40268-018-0226-z

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