Plasma ctDNA RAS mutation analysis for the diagnosis and treatment monitoring of metastatic colorectal cancer patients

BACKGROUND: RAS assessment is mandatory for therapy decision in metastatic colorectal cancer (mCRC) patients. This determination is based on tumor tissue, however, genotyping of circulating tumor (ct)DNA offers clear advantages as a minimally invasive method that represents tumor heterogeneity. Our...

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Detalles Bibliográficos
Autores principales: Vidal, J, Muinelo, L, Dalmases, A, Jones, F, Edelstein, D, Iglesias, M, Orrillo, M, Abalo, A, Rodríguez, C, Brozos, E, Vidal, Y, Candamio, S, Vázquez, F, Ruiz, J, Guix, M, Visa, L, Sikri, V, Albanell, J, Bellosillo, B, López, R, Montagut, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834035/
https://www.ncbi.nlm.nih.gov/pubmed/28419195
http://dx.doi.org/10.1093/annonc/mdx125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834035/
https://www.ncbi.nlm.nih.gov/pubmed/28419195
http://dx.doi.org/10.1093/annonc/mdx125

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