Concordance of blood- and tumor-based detection of RAS mutations to guide anti-EGFR therapy in metastatic colorectal cancer

BACKGROUND: Circulating tumor DNA (ctDNA) is a potential source for tumor genome analysis. We explored the concordance between the mutational status of RAS in tumor tissue and ctDNA in metastatic colorectal cancer (mCRC) patients to establish eligibility for anti-epidermal growth factor receptor (EG...

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Detalles Bibliográficos
Autores principales: Grasselli, J, Elez, E, Caratù, G, Matito, J, Santos, C, Macarulla, T, Vidal, J, Garcia, M, Viéitez, J M, Paéz, D, Falcó, E, Lopez Lopez, C, Aranda, E, Jones, F, Sikri, V, Nuciforo, P, Fasani, R, Tabernero, J, Montagut, C, Azuara, D, Dienstmann, R, Salazar, R, Vivancos, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834108/
https://www.ncbi.nlm.nih.gov/pubmed/28368441
http://dx.doi.org/10.1093/annonc/mdx112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834108/
https://www.ncbi.nlm.nih.gov/pubmed/28368441
http://dx.doi.org/10.1093/annonc/mdx112

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