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The conundrum of indeterminate QuantiFERON-TB Gold results before anti-tumor necrosis factor initiation

BACKGROUND: Tumor necrosis factor alpha (TNFα) is a key cytokine in both the pathogenesis of inflammatory bowel disease (IBD) and rheumatoid arthritis (RA) and the host defense against tuberculosis (TB). Consequently, anti-TNFα medications result in an increased risk of latent TB infection (LTBI) re...

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Detalles Bibliográficos
Autores principales: Hakimian, Shahrad, Popov, Yevgeniy, Rupawala, Abbas H, Salomon-Escoto, Karen, Hatch, Steven, Pellish, Randall
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834167/
https://www.ncbi.nlm.nih.gov/pubmed/29520131
http://dx.doi.org/10.2147/BTT.S150958