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Sonic Hedgehog Signaling Regulates Hematopoietic Stem/Progenitor Cell Activation during the Granulopoietic Response to Systemic Bacterial Infection

Activation and reprogramming of hematopoietic stem/progenitor cells play a critical role in the granulopoietic response to bacterial infection. Our current study determined the significance of Sonic hedgehog (SHH) signaling in the regulation of hematopoietic precursor cell activity during the host d...

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Detalles Bibliográficos
Autores principales: Shi, Xin, Wei, Shengcai, Simms, Kevin J., Cumpston, Devan N., Ewing, Thomas J., Zhang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834434/
https://www.ncbi.nlm.nih.gov/pubmed/29535725
http://dx.doi.org/10.3389/fimmu.2018.00349