Accessory and Central α-helices of Complexin Selectively Activate Ca(2+) Triggering of Synaptic Exocytosis

Complexins, binding to assembling soluble NSF-attachment protein receptor (SNARE) complexes, activate Ca(2+) triggered exocytosis and clamp spontaneous release in the presynaptic terminal. Functions of complexin are structural dependent and mechanistically distinct. To further understand the functio...

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Detalles Bibliográficos
Autores principales: Yu, Yi, Chen, Su, Mo, Xiaoqiang, Gong, Jihong, Li, Chenhong, Yang, Xiaofei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834437/
https://www.ncbi.nlm.nih.gov/pubmed/29535609
http://dx.doi.org/10.3389/fnmol.2018.00061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834437/
https://www.ncbi.nlm.nih.gov/pubmed/29535609
http://dx.doi.org/10.3389/fnmol.2018.00061

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