Mahanine drives pancreatic adenocarcinoma cells into endoplasmic reticular stress-mediated apoptosis through modulating sialylation process and Ca(2+)-signaling

Endoplasmic reticulum (ER) stress results from protein unfolding/misfolding during cellular maturation, which requires a coordinated action of several chaperones and enzymes and Ca(2+) signalling. ER-stress possibly has a positive effect on survival of pancreatic cancer cell. Therefore, detailed ins...

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Detalles Bibliográficos
Autores principales: Sarkar Bhattacharya, Sayantani, Mandal, Chandan, Albiez, Reinhard Schwartz, Samanta, Suman Kumar, Mandal, Chitra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834441/
https://www.ncbi.nlm.nih.gov/pubmed/29500369
http://dx.doi.org/10.1038/s41598-018-22143-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834441/
https://www.ncbi.nlm.nih.gov/pubmed/29500369
http://dx.doi.org/10.1038/s41598-018-22143-w

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