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Mahanine drives pancreatic adenocarcinoma cells into endoplasmic reticular stress-mediated apoptosis through modulating sialylation process and Ca(2+)-signaling
Endoplasmic reticulum (ER) stress results from protein unfolding/misfolding during cellular maturation, which requires a coordinated action of several chaperones and enzymes and Ca(2+) signalling. ER-stress possibly has a positive effect on survival of pancreatic cancer cell. Therefore, detailed ins...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834441/ https://www.ncbi.nlm.nih.gov/pubmed/29500369 http://dx.doi.org/10.1038/s41598-018-22143-w |