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Astrocytic JWA deletion exacerbates dopaminergic neurodegeneration by decreasing glutamate transporters in mice

Astrocytic JWA exerts neuroprotective roles by alleviating oxidative stress and inhibiting inflammation. However, the molecular mechanisms of how astrocytic JWA is involved in dopaminergic neurodegeneration in Parkinson’s disease (PD) remain largely unknown. In this study, we found that astrocyte-sp...

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Detalles Bibliográficos
Autores principales: Wang, Rihua, Zhao, Xue, Xu, Jin, Wen, Yifan, Li, Aiping, Lu, Ming, Zhou, Jianwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834463/
https://www.ncbi.nlm.nih.gov/pubmed/29500411
http://dx.doi.org/10.1038/s41419-018-0381-8