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Early Growth Response Gene 2-Expressing CD4(+)LAG3(+) Regulatory T Cells: The Therapeutic Potential for Treating Autoimmune Diseases

Regulatory T cells (Tregs) are necessary for the maintenance of immune tolerance. Tregs are divided into two major populations: one is thymus derived and the other develops in the periphery. Among these Tregs, CD4(+)CD25(+) Tregs, which mainly originate in the thymus, have been extensively studied....

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Detalles Bibliográficos
Autores principales: Okamura, Tomohisa, Yamamoto, Kazuhiko, Fujio, Keishi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834469/
https://www.ncbi.nlm.nih.gov/pubmed/29535721
http://dx.doi.org/10.3389/fimmu.2018.00340