Metabolic Reprogramming in Amyotrophic Lateral Sclerosis

Mitochondrial dysfunction in the spinal cord is a hallmark of amyotrophic lateral sclerosis (ALS), but the neurometabolic alterations during early stages of the disease remain unknown. Here, we investigated the bioenergetic and proteomic changes in ALS mouse motor neurons and patients’ skin fibrobla...

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Detalles Bibliográficos
Autores principales: Szelechowski, M., Amoedo, N., Obre, E., Léger, C., Allard, L., Bonneu, M., Claverol, S., Lacombe, D., Oliet, S., Chevallier, S., Le Masson, G., Rossignol, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834494/
https://www.ncbi.nlm.nih.gov/pubmed/29500423
http://dx.doi.org/10.1038/s41598-018-22318-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834494/
https://www.ncbi.nlm.nih.gov/pubmed/29500423
http://dx.doi.org/10.1038/s41598-018-22318-5

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