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Significance of risk polymorphisms for depression depends on stress exposure

Depression is a polygenic and multifactorial disorder where environmental effects exert a significant impact, yet most genetic studies do not consider the effect of stressors which may be one reason for the lack of replicable results in candidate gene studies, GWAS and between human studies and anim...

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Detalles Bibliográficos
Autores principales: Gonda, Xenia, Hullam, Gabor, Antal, Peter, Eszlari, Nora, Petschner, Peter, Hökfelt, Tomas GM, Anderson, Ian Muir, Deakin, John Francis William, Juhasz, Gabriella, Bagdy, Gyorgy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834495/
https://www.ncbi.nlm.nih.gov/pubmed/29500446
http://dx.doi.org/10.1038/s41598-018-22221-z