A macromolecular approach to eradicate multidrug resistant bacterial infections while mitigating drug resistance onset

Polymyxins remain the last line treatment for multidrug-resistant (MDR) infections. As polymyxins resistance emerges, there is an urgent need to develop effective antimicrobial agents capable of mitigating MDR. Here, we report biodegradable guanidinium-functionalized polycarbonates with a distinctiv...

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Detalles Bibliográficos
Autores principales: Chin, Willy, Zhong, Guansheng, Pu, Qinqin, Yang, Chuan, Lou, Weiyang, De Sessions, Paola Florez, Periaswamy, Balamurugan, Lee, Ashlynn, Liang, Zhen Chang, Ding, Xin, Gao, Shujun, Chu, Collins Wenhan, Bianco, Simone, Bao, Chang, Tong, Yen Wah, Fan, Weimin, Wu, Min, Hedrick, James L., Yang, Yi Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834525/
https://www.ncbi.nlm.nih.gov/pubmed/29500445
http://dx.doi.org/10.1038/s41467-018-03325-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834525/
https://www.ncbi.nlm.nih.gov/pubmed/29500445
http://dx.doi.org/10.1038/s41467-018-03325-6

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