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Deletion of the Syncytin A receptor Ly6e impairs syncytiotrophoblast fusion and placental morphogenesis causing embryonic lethality in mice

Fetal growth and survival is dependent on the elaboration and propinquity of the fetal and maternal circulations within the placenta. Central to this is the formation of the interhaemal membrane, a multi-cellular lamina facilitating exchange of oxygen, nutrients and metabolic waste products between...

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Detalles Bibliográficos
Autores principales: Langford, Michael B., Outhwaite, Jennifer E., Hughes, Martha, Natale, David R. C., Simmons, David G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834536/
https://www.ncbi.nlm.nih.gov/pubmed/29500366
http://dx.doi.org/10.1038/s41598-018-22040-2