Hydroxychloroquine attenuates renal ischemia/reperfusion injury by inhibiting cathepsin mediated NLRP3 inflammasome activation

Inflammation is a major contributor to the pathogenesis of ischemic acute kidney injury (AKI), which complicates the post-operative outcomes of large numbers of hospitalized surgical patients. Hydroxychloroquine (HCQ), a well-known anti-malarial drug, is commonly used in clinical practice for its an...

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Detalles Bibliográficos
Autores principales: Tang, Tao-Tao, Lv, Lin-Li, Pan, Ming-Ming, Wen, Yi, Wang, Bin, Li, Zuo-Lin, Wu, Min, Wang, Feng-Mei, Crowley, Steve D, Liu, Bi-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834539/
https://www.ncbi.nlm.nih.gov/pubmed/29500339
http://dx.doi.org/10.1038/s41419-018-0378-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834539/
https://www.ncbi.nlm.nih.gov/pubmed/29500339
http://dx.doi.org/10.1038/s41419-018-0378-3

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