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Improved isolation strategies to increase the yield and purity of human urinary exosomes for biomarker discovery

Circulating miRNAs are detected in extracellular space and body fluids such as urine. Circulating RNAs can be packaged in secreted urinary extracellular vesicles (uEVs) and thus protected from degradation. Urinary exosome preparations might contain specific miRNAs, relevant as biomarkers in renal an...

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Detalles Bibliográficos
Autores principales: Gheinani, Ali Hashemi, Vögeli, Mike, Baumgartner, Ulrich, Vassella, Erik, Draeger, Annette, Burkhard, Fiona C., Monastyrskaya, Katia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834546/
https://www.ncbi.nlm.nih.gov/pubmed/29500443
http://dx.doi.org/10.1038/s41598-018-22142-x