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Abaloparatide, a novel PTH receptor agonist, increased bone mass and strength in ovariectomized cynomolgus monkeys by increasing bone formation without increasing bone resorption

SUMMARY: Abaloparatide, a novel PTH1 receptor agonist, increased bone formation in osteopenic ovariectomized cynomolgus monkeys while increasing cortical and trabecular bone mass. Abaloparatide increased bone strength and maintained or enhanced bone mass-strength relationships, indicating preserved...

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Detalles Bibliográficos
Autores principales: Doyle, N., Varela, A., Haile, S., Guldberg, R., Kostenuik, P. J., Ominsky, M. S., Smith, S. Y., Hattersley, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer London 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834552/
https://www.ncbi.nlm.nih.gov/pubmed/29260289
http://dx.doi.org/10.1007/s00198-017-4323-6